Welcome to iChemical.com!

In the below part, please select the country you want us to ship to: Please note that once you've selected a shipping country, all pricing information on our website will be automatically updated to include door-to-door shipping to the country you specified.

    OK
    Get Quote Login
    252574-03-1

    Catalog No. EBD9625

    CAS 252574-03-1

    Name (3S,4S)-tert-Butyl 3-(benzylamino)-4-hydroxypyrrolidine-1-carboxylate

    Get Quote
    Basic Information

    Synonyms: (3S,4S)-N-Boc-3-(benzylamino)-4-hydroxypyrrolidine (3S,4S)-3-Hydroxy-4-[(phenylmethyl)amino]-1-pyrrolidinecarboxylicacid1,1-dimethylethylester tert-butyl(3S,4S)-3-(benzylamino)-4-hydroxypyrrolidine-1-carboxylate (3S,4S)-tert-Butyl3-(benzylamino)-4-hydroxypyrrolidine-1-carboxylate

    Molecular Formula: C16H24N2O3

    Molecular Weight: 292.37

    Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Heterocyclic Intermediates Synthetic Chemistry > Organic Building Blocks > Amines

    Product Description:
    (3S,4S)-N-Boc-3-Benzylamino-4-hydroxypyrrolidine is a chiral, protected pyrrolidine derivative. It features a Boc-protected secondary amine, a benzylamino substituent, and a hydroxyl group on a saturated five-membered heterocyclic ring. The compound is characterized by two defined stereocenters in the (3S,4S) configuration, making it a valuable chiral building block. This compound is primarily used as a key synthetic intermediate in pharmaceutical research and development. Its pyrrolidine scaffold is a privileged structure found in numerous bioactive molecules. The presence of multiple functional groups allows for diverse chemical modifications, enabling its incorporation into more complex target structures, particularly in the synthesis of potential drug candidates. As a specialized chiral intermediate, it is not a commodity chemical but is supplied for research purposes. Its synthesis and handling require standard precautions for organic compounds, particularly those containing amine functionalities.
    Physical Properties

    Boiling Point: 424.6°C at 760 mmHg

    Flash Point: 210.6°C

    Density: 1.16

    mg g kg ml l t