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    2482-00-0

    Catalog No. EBD7783

    CAS 2482-00-0

    Name 1-Amino-4-guanidinobutane sulfate salt

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    Basic Information

    Synonyms: (4-aminobutyl)guanidiniumsulphate Agmatinesulfate 2-(4-aminobutyl)guanidine 2-(4-aminobutyl)guanidinesulfate (4-Aminobutyl)guanidinesulphate (4-Aminobutyl)guanidiniumsulfate AgmatineSulphate 1-Amino-4-guanidinobutanesulfatesalt n-(4-aminobutyl)guanidinesulfate n-(4-aminobutyl)guanidinesulfatesalt 1-amino-4-guanidinobutanesulfate 1-amino-4-guanidobutanesulfate 4-guanidinobutanesulfate 4-guanidino-butylaminesulfate 4-guanidino-butylaminesulfatesalt

    Molecular Formula: C5H16N4O4S

    Molecular Weight: 228.27

    MDL Number: MFCD00013109

    Categories: Functional Chemicals > Food Additives and Ingredients > Other Functional Food Ingredients Medicinal Chemistry > Biochemicals and Life Science Reagents > Peptides and Peptidomimetics Medicinal Chemistry > Biochemicals and Life Science Reagents > Amino Acids and Derivatives

    Product Description:
    Agmatine sulfate is the sulfate salt of agmatine, a naturally occurring polyamine formed by the decarboxylation of L-arginine via arginine decarboxylase. Structurally, it consists of a guanidino group attached to a butylamine chain, and its sulfate salt form enhances water solubility and stability. As a biogenic amine, agmatine acts as a neuromodulator and signaling molecule in the central nervous system. It functions as an agonist at imidazoline I1 and I2 receptors, an antagonist at N-methyl-D-aspartate (NMDA) receptors, and an inhibitor of nitric oxide synthase (NOS). These properties make it a valuable research tool for studying neuroprotection, pain modulation, and cardiovascular regulation. In biomedical research, it is widely used as an *in vivo* research reagent to investigate its potential therapeutic effects in conditions such as diabetic neuropathy, depression, and addiction. Additionally, it has been explored as a potential active pharmaceutical ingredient (API) for drug development targeting metabolic and neurological disorders.
    Physical Properties

    Color: white to off-white

    Melting Point: 234-238 °C(lit.)

    Boiling Point: 281.4 °C at 760 mmHg

    Flash Point: 124 °C

    Solubility: H2O: 50 mg/mL

    Storage: −20°C

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