2,3-Dichloropyridine, CAS No. 2402-77-9

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2402-77-9

Catalog No. EBD541050

CAS 2402-77-9

Name 2,3-Dichloropyridine

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Basic Information

Synonyms: 2,3-dichloro-pyridin 2,3-dichloropyridine147.99 2,3-dichloropyridine,99% 2,3-dichloropyridine2,3-dichloropyridine 2,3-dichloropydine 2,3-dichloropyridine,98% 3-dichloropyridine 2,3-Dichloropyridine 2,3-dichlopyridine 2,3-dichloro-pyridine pyridine,2,3-dichloro-

Molecular Formula: C5H3Cl2N

Molecular Weight: 147.99

MDL Number: MFCD00006229

Categories: Synthetic Chemistry > Organic Building Blocks > Halogenated Compounds Medicinal Chemistry > Pharmaceutical Intermediates > Heterocyclic Intermediates

Product Description:

2,3-Dichloropyridine is an organic compound featuring a pyridine ring substituted with chlorine atoms at the 2- and 3-positions. It is a halogenated heterocyclic building block with a molecular formula of C5H3Cl2N. This compound typically appears as a white to off-white crystalline solid. Its primary utility lies in organic synthesis, where it serves as a versatile intermediate. The presence of two chlorine atoms at adjacent positions on the pyridine ring makes it a valuable precursor for the synthesis of more complex heterocyclic systems and functionalized pyridines through nucleophilic aromatic substitution or metal-catalyzed cross-coupling reactions. It is notably used in the pharmaceutical industry for the preparation of various active pharmaceutical ingredients (APIs) and agrochemicals. As a halogenated pyridine derivative, it requires careful handling due to its potential toxicity and irritant properties. It is commonly employed in research and development settings for constructing molecules with potential biological activity.

Physical Properties

Melting Point: 64-67 °C(lit.)

Boiling Point: 192.5 °C at 760 mmHg

Flash Point: 87.5 °C

Density: 1.388 g/cm3

Solubility: slightly soluble

Analytical Data

Appearance: White to slightly beige crystalline powder