N-Boc-L-lysine methyl ester hydrochloride, CAS No. 2389-48-2

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2389-48-2

Catalog No. EBD21230

CAS 2389-48-2

Name N-Boc-L-lysine methyl ester hydrochloride

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Basic Information

Synonyms: H-Lys(Boc)-OMe.HCl H-Lys(Boc)-OMe*HCl H-Lys(Boc)-OMehydrochloride N-EPSILON-TERT-BUTOXYCARBONYL-L-LYSINEMETHYLESTERHYDROCHLORIDE (2S)-6-[(tert-butoxycarbonyl)amino]-1-methoxy-1-oxohexan-2-aminiumchloride methylN²-(tert-butoxycarbonyl)-L-lysinatehydrochloride N-Boc-L-lysinemethylesterhydrochloride H-Lys(Boc)-OMe·HCl Nepsilon-Tert-Butoxycarbonyl-L-LysineMethylEsterHydrochloride (S)-2-Amino-6-tert-butoxycarbonylamino-hexanoicacidmethylesterhydrochloride n-epsilon-l-lysinemethylesterhydrochloridesalt n-epsilon-boc-l-lysinemethylesterhydrochloride n-epsilon-boc-l-lysinemethylesterhydrocloridesalt n-epsilon-t-boc-l-lysinemethylesterhydrochloride n-epsilon-t-butoxycarbonyl-l-lysinemethylesterhydrochloride lysine(boc)-omehcl H-Lys(Boc)-OMeHCl (2S)-6-[(tert-butoxycarbonyl)am

Molecular Formula: C12H25ClN2O4

Molecular Weight: 296.79

MDL Number: MFCD00076959

Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Drug Synthesis Building Blocks Synthetic Chemistry > Organic Building Blocks > Amines

Product Description:

N-Boc-L-lysine methyl ester hydrochloride is a protected derivative of the essential amino acid L-lysine. It features a tert-butoxycarbonyl (Boc) group protecting the alpha-amino functionality and a methyl ester protecting the carboxylic acid group, with the side-chain amino group remaining as the hydrochloride salt. This configuration makes it a versatile and stable building block for peptide synthesis and medicinal chemistry. Its primary application is as a key intermediate in the synthesis of peptides and peptidomimetics, particularly those requiring the incorporation of a lysine residue. The Boc-protected amine allows for orthogonal deprotection strategies in solid-phase and solution-phase peptide synthesis. It is widely used in the research and development of pharmaceutical compounds, including potential therapeutics targeting various diseases. This compound is a commercially available, high-purity reagent essential for constructing complex molecular architectures in drug discovery. Proper handling requires standard laboratory safety precautions for handling fine chemicals.

Physical Properties

Boiling Point: 364.6°Cat760mmHg

Flash Point: 174.3°C

Storage: 2-8°C