2-Chloropyridine-5-carboxaldehyde, CAS No. 23100-12-1

Welcome to iChemical.com!

In the below part, please select the country you want us to ship to: Please note that once you've selected a shipping country, all pricing information on our website will be automatically updated to include door-to-door shipping to the country you specified.

North America

South America

Africa

Europe

Asia

Oceania

23100-12-1

Catalog No. EBD321107

CAS 23100-12-1

Name 2-Chloropyridine-5-carboxaldehyde

Get Quote

Basic Information

Synonyms: 6-ChloroNicotinaldehyde 2-Chloro-5-pyridinecarbaldehyde 2-Chloropyridine-5-carbaldehyde 6-chloropyridine-3-carbaldehyde 2-Chloro-5-formylpyridine 6-Chloropyridine-3-carboxaldehyde 2-Chloropyridine-5-carboxaldehyde

Molecular Formula: C6H4ClNO

Molecular Weight: 141.56

MDL Number: MFCD03095223

Categories: Synthetic Chemistry > Organic Building Blocks > Halogenated Compounds Synthetic Chemistry > Organic Building Blocks > Aldehydes and Ketones Medicinal Chemistry > Pharmaceutical Intermediates > Heterocyclic Intermediates

Product Description:

2-Chloropyridine-5-carboxaldehyde is a heterocyclic building block featuring a pyridine ring substituted with a chlorine atom at the 2-position and an aldehyde group at the 5-position. Its molecular formula is C6H4ClNO, and it appears as a white to light yellow crystalline powder. This compound is primarily utilized as a key intermediate in the synthesis of pharmaceuticals, particularly in the development of antiviral, anticancer, and central nervous system agents. The aldehyde group enables further functionalization through reactions such as reductive amination, condensation, and cross-coupling, while the chlorine atom serves as a handle for transition-metal-catalyzed transformations like Suzuki or Buchwald-Hartwig couplings. As a versatile synthetic building block, it is also widely employed in organic synthesis for constructing complex heterocyclic structures and agrochemical intermediates. It should be stored under inert atmosphere and protected from light to prevent degradation.

Physical Properties

Melting Point: 77-81 °C(lit.)

Boiling Point: 249.3 ºC at 760 mmHg

Flash Point: 104.6 ºC

Density: 1.332 g/cm3

Analytical Data

Appearance: off white powder