2,3,4,5-Tetrahydro-1H-1,5-methanobenzo[d]azepine hydrochloride, CAS No. 230615-52-8

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230615-52-8

Catalog No. EBD16714

CAS 230615-52-8

Name 2,3,4,5-Tetrahydro-1H-1,5-methanobenzo[d]azepine hydrochloride

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Basic Information

Synonyms: 2,3,4,5-tetrahydro-1,5-Methano-1H-3-benzazepine,hydrochloride(1:1) 2,3,4,5-tetrahydro-1,5-Methano-1H-3-benzazepine,hydrochloride 2,3,4,5-Tetrahydro-1H-1,5-methano-3-benzazepinehydrochlortde 2,3,4,5-Tetrahydro-1,5-methano-1H-3-benzazepinehydrochloride 2,3,4,5-tetrahydro-1H-1,5-methano-3-benzazepinehydrochloride(1:1) 2,3,4,5-Tetrahydro-1H-1,5-methanobenzo[d]azepinehydrochloride

Molecular Formula: C11H14ClN

Molecular Weight: 195.69

MDL Number: MFCD11042279

Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Heterocyclic Intermediates Medicinal Chemistry > APIs and Their Salts > Nervous System Drugs

Product Description:

2,3,4,5-Tetrahydro-1,5-methano-1H-3-benzazepine hydrochloride is a heterocyclic organic compound featuring a benzazepine core structure. It serves as a key synthetic intermediate in the preparation of various pharmacologically active molecules. This compound is notably utilized in the synthesis of Lorcaserin hydrochloride (Belviq), a selective serotonin 2C (5-HT2C) receptor agonist. Lorcaserin was approved as an anti-obesity drug, functioning by activating 5-HT2C receptors in the brain to promote satiety and reduce food intake. The benzazepine scaffold is crucial for its biological activity. As a specialized pharmaceutical intermediate, its primary application is confined to the research and development of central nervous system (CNS) targeting drugs. Handling requires standard laboratory safety precautions for organic salts.

Physical Properties

Boiling Point: 277.9 °C at 760 mmHg

Flash Point: 128.9 °C