(S)-(+)-2-Amino-3-hydroxy-3-methylbutanoic acid, CAS No. 2280-27-5

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2280-27-5

Catalog No. EBD21330

CAS 2280-27-5

Name (S)-(+)-2-Amino-3-hydroxy-3-methylbutanoic acid

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Basic Information

Synonyms: 3-hydroxy-l-valine (r)-(-)-2-amino-3-hydroxy-3-methylbutanoicacid(e.e.) (r)-(-)-2-amino-3-hydroxy-3-methylbutanoicacid99%(99+%e.e.) (s)-(+)-2-amino-3-hydroxy-3-methylbutanoicacid,98%,ee:94% (s)-(+)-2-amino-3-hydroxy-3-methylbutanoicacid,94%ee (2s)-2-amino-3-hydroxy-3-methylbutanoicacid 3-hydroxy-D-valine (S)-2-Amino-3-Hydroxy-3-MethylbutanoicAcid (S)-(+)-2-Amino-3-Hydroxy-3-MethylbutanoicAcid L(+)-Hydroxyvaline

Molecular Formula: C5H11NO3

Molecular Weight: 133.15

MDL Number: MFCD00800535

Categories: Medicinal Chemistry > Biochemicals and Life Science Reagents > Amino Acids and Derivatives Synthetic Chemistry > Organic Building Blocks > Amines

Product Description:

(S)-(+)-2-Amino-3-hydroxy-3-methylbutyric acid is a non-proteinogenic amino acid derivative. It features a chiral center at the α-carbon and a tertiary alcohol group on the β-carbon, making it a valuable chiral building block. This compound is structurally related to the amino acid threonine but with an additional methyl group at the β-position. This amino acid derivative serves as a key intermediate in the synthesis of various biologically active compounds. Its primary application is in medicinal chemistry research, particularly as a precursor for the synthesis of peptide-based drugs and enzyme inhibitors. The presence of both amino and hydroxyl functional groups allows for versatile chemical modifications, enabling its incorporation into complex molecular architectures designed for pharmaceutical applications. Due to its chiral nature and functional group diversity, it is also employed in asymmetric synthesis and as a ligand precursor in catalysis. It is commercially available as a high-purity reagent for research and development purposes in both academic and industrial laboratories.

Physical Properties

Boiling Point: 317.3 °C at 760 mmHg

Flash Point: 145.7 °C

Density: 1.24 g/cm3

Solubility: SOLUBLE

Analytical Data

Appearance: white powder