3,4-Dihydro-7-hydroxy-2(1H)-quinolinone, CAS No. 22246-18-0

Welcome to iChemical.com!

In the below part, please select the country you want us to ship to: Please note that once you've selected a shipping country, all pricing information on our website will be automatically updated to include door-to-door shipping to the country you specified.

North America

South America

Africa

Europe

Asia

Oceania

22246-18-0

Catalog No. EBD11037

CAS 22246-18-0

Name 3,4-Dihydro-7-hydroxy-2(1H)-quinolinone

Get Quote

Basic Information

Synonyms: 7-Hydroxyquinolinone 7-Hydroxy-2-(1H)-quinolinone 7-Hydroxycarbostyril 7-hydroxy-3,4-dihydro-2(1h)-quinolinone 2(1H)-Quindinone,3,4-dohydro-7Hydroxy 3,4-Dihydro-7-hydroxy-2(1H)-quinolinone 3,4-Dihydro-7-hydroxycarbostyril 7-Hydroxy-3,4-Dihydro-2-(1H)-Quinoline 7-Hydroxy-3,4-dihydro-1H-quinolin-2-one 7-Hydroxy-3,4-dihydroquinolone 7-Hydroxy-3,4-dihydrocarbostyril 7-hydroxy-3,4-dihydroquinolin-2(1H)-one 7-Hydroxyquinolin-2(1H)-One 3,4-Dihydro-7-Hydroxy-2(1H)-Quinlinone 7-Hydroxy-1,2,3,4-tetrahydro-2-quinolinone 7-hydroxy-1,2-dihydroquinolin-2-one 7-hydroxy-1H-quinolin-2-one

Molecular Formula: C9H9NO2

Molecular Weight: 163.17

MDL Number: MFCD06410891

Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Heterocyclic Intermediates

Product Description:

3,4-Dihydro-7-hydroxy-2(1H)-quinolinone is a heterocyclic organic compound featuring a fused benzene and dihydro-2-quinolinone ring system with a hydroxyl substituent. It serves as a versatile and important synthetic building block in medicinal chemistry. Its primary application is as a key intermediate in the synthesis of various pharmacologically active compounds. Notably, it is a crucial precursor in the production of certain antimalarial drugs, such as amodiaquine and its analogs. The hydroxyl and carbonyl groups on the quinolinone core provide reactive sites for further chemical modifications, enabling the construction of complex molecular architectures. This compound is a fundamental scaffold for generating libraries of bioactive molecules targeting diverse therapeutic areas. Its utility underscores its significance in the research and development of new pharmaceutical agents.

Physical Properties

Melting Point: 233-237 °C

Boiling Point: 403.7 °C at 760 mmHg

Flash Point: 198 °C

Density: 1.282 g/cm3

Analytical Data

Appearance: Pale yellow powder