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    221037-98-5

    Catalog No. EBD44377

    CAS 221037-98-5

    Name 3-Iodophenylboronic acid

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    Basic Information

    Synonyms: 3-iodophenylboronicacid boronicacid,(3-iodophenyl)-(9ci)

    Molecular Formula: C6H6BIO2

    Molecular Weight: 247.83

    MDL Number: MFCD01319015

    Categories: Synthetic Chemistry > Organic Building Blocks > Boronic Acids and Boronic Esters Synthetic Chemistry > Organic Building Blocks > Halogenated Compounds

    Product Description:
    3-Iodophenylboronic acid is an organoboron compound featuring both a boronic acid group and an iodine substituent on the phenyl ring. This bifunctional structure makes it a versatile building block in synthetic organic chemistry, particularly in cross-coupling reactions. Its primary application is as a key reagent in Suzuki-Miyaura cross-coupling reactions. The boronic acid group readily participates in palladium-catalyzed coupling with aryl or vinyl halides, while the iodine atom serves as an excellent leaving group for further functionalization via other metal-catalyzed reactions (e.g., Sonogashira, Heck, or Buchwald-Hartwig couplings). This dual reactivity allows for the sequential, modular construction of complex biaryl and conjugated systems, which are common scaffolds in pharmaceuticals, agrochemicals, and organic materials. The compound is a solid and should be stored under inert conditions to prevent protodeboronation. It is widely available from chemical suppliers as a standard synthetic intermediate for research and development purposes.
    Physical Properties

    Melting Point: 195-197 °C(lit.)

    Boiling Point: 358.8 °C at 760 mmHg

    Flash Point: 170.8 °C

    Density: 1.95 g/cm3

    Storage: 0-6°C

    Analytical Data

    Appearance: White to light yellow crystal powder

    mg g kg ml l t