1-(Dimethoxymethyl)-4-methoxybenzene, CAS No. 2186-92-7

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2186-92-7

Catalog No. EBD33645

CAS 2186-92-7

Name 1-(Dimethoxymethyl)-4-methoxybenzene

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Basic Information

Synonyms: p-(dimethoxymethyl)anisole 1-(dimethoxymethyl)-4-methoxybenzene 1,1,4-trimethoxybenzene 1-(dimethoxymethyl)4-methoxybenzene p-anisaldehydediethylacetal 1-(dimethoxymethyl)-4-methoxy-benzen 1-(dimethoxymethyl)-4-methoxy-benzene anisicaldehydedimethylacetal p-anisaldehydedimethylacetal 4-methoxybenzaldehydedimethylacetal anisaldehydedimethylacetal anisicaldehydedma

Molecular Formula: C10H14O3

Molecular Weight: 182.22

MDL Number: MFCD00036507

Categories: Synthetic Chemistry > Organic Building Blocks > Aldehydes and Ketones Synthetic Chemistry > Basic Synthetic Reagents > Protecting and Deprotecting Reagents

Product Description:

4-Methoxybenzaldehyde dimethyl acetal is an organic compound with the molecular formula C10H14O3. It is a dimethyl acetal derivative of 4-methoxybenzaldehyde (anisaldehyde), where the aldehyde group is protected as an acetal. This compound typically appears as a colorless to pale yellow liquid. Its primary role in synthetic chemistry is as a protected form of the aldehyde functional group. The acetal group is stable under basic and nucleophilic conditions but can be readily cleaved under acidic aqueous conditions to regenerate the parent aldehyde, 4-methoxybenzaldehyde. This makes it a valuable synthon and a protecting group reagent in multi-step organic synthesis. It is used as a building block for the preparation of more complex molecules, particularly in the synthesis of pharmaceuticals, fragrances, and liquid crystals, where the anisaldehyde moiety is a key structural component. As a reagent, it offers advantages in handling and storage compared to the free aldehyde, which can be prone to oxidation. Its use allows for selective reactions at other sites of a molecule without affecting the masked carbonyl group.

Physical Properties

Boiling Point: 85-87 °C/0.1 mmHg(lit.)

Flash Point: 114 °C

Density: 1.07 g/mL at 20 °C(lit.)

Refractivity: n20/D 1.505

Storage: 2-8°C