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    2185-03-7

    Catalog No. EBD51674

    CAS 2185-03-7

    Name L-Homoserine lactone hydrochloride

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    Basic Information

    Synonyms: h-l-hse-lactonehcl hselactonehcl hsl homoserinelactonehydrochloride homoserine(l-)lactonehcl l-(-)-homoserinelactonehydrochloride l-(-)-a-amino-g-butyrolactonehydrochloride (S)-(+)-α-amino-γ-butyrolactonehydrochloride (3S)-3-aminodihydrofuran-2(3H)-onehydrochloride 2-oxo-2,3-dihydrofuran-3-aminiumchloride (S)-(-)-alpha-Amino-gamma-butyrolactonehydrochloride L-Homoserinelactonehydrochloride

    Molecular Formula: C4H8ClNO2

    Molecular Weight: 137.56

    MDL Number: MFCD00058172

    Categories: Medicinal Chemistry > Biochemicals and Life Science Reagents > Amino Acids and Derivatives Synthetic Chemistry > Organic Building Blocks > Other Organic Building Blocks

    Product Description:
    L-Homoserine lactone hydrochloride is a derivative of the non-proteinogenic amino acid L-homoserine. It is a cyclic ester (lactone) of homoserine, existing as a hydrochloride salt, which enhances its stability and solubility for research and synthetic applications. This compound serves as a crucial chiral building block in organic synthesis, particularly for the preparation of complex molecules. Its primary significance lies in the pharmaceutical and life sciences fields, where it is used as an intermediate in the synthesis of various biologically active compounds, including antibiotics, enzyme inhibitors, and other drug candidates that incorporate modified amino acid structures. As a protected or activated form of homoserine, it facilitates the introduction of the homoserine moiety into peptides and other molecular frameworks under controlled conditions. It is a valuable reagent for researchers in medicinal chemistry and chemical biology.
    Physical Properties

    Melting Point: 210-220 °C (dec.)(lit.)

    Boiling Point: 257.1 °C at 760 mmHg

    Flash Point: 120.1 °C

    Solubility: soluble

    Refractivity: -26 ° (C=0.2, H2O)

    Storage: 2-8°C

    Analytical Data

    Appearance: white solid

    mg g kg ml l t