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    21752-36-3

    Catalog No. EBD7340

    CAS 21752-36-3

    Name (S)-2-((1-Phenylethyl)carbamoyl)benzoic acid

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    Basic Information

    Synonyms: (S)-(-)-N-(alpha-Methylbenzyl)phthalamidicacid (S)-o-(((1-Phenylethyl)amino)carbonyl)benzoicacid 2-{[(1S)-1-phenylethyl]carbamoyl}benzoicacid (S)-2-((1-Phenylethyl)carbamoyl)benzoicacid

    Molecular Formula: C16H15NO3

    Molecular Weight: 269.3

    MDL Number: MFCD00078492

    Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Chiral Intermediates Synthetic Chemistry > Organic Building Blocks > Amines

    Product Description:
    (S)-(-)-N-(1-Phenylethyl)phthalimide, with CAS number 21752-36-3, is a chiral organic compound. It is structurally characterized as a phthalimide derivative bearing a (S)-1-phenylethyl substituent on the nitrogen atom. This compound is a solid at room temperature. This molecule is primarily utilized as a chiral intermediate or building block in organic synthesis, particularly in the pharmaceutical industry. The presence of the chiral center and the phthalimide group makes it valuable for constructing more complex, enantiomerically pure molecules. It can serve as a precursor or a chiral auxiliary in the synthesis of active pharmaceutical ingredients (APIs) and other biologically active compounds where stereochemistry is crucial. Its application is rooted in its role as a versatile synthon. The phthalimide group can act as a protected amine or be further functionalized, while the chiral phenylethyl moiety can influence the stereochemical outcome of subsequent reactions. It is a specialized reagent for research and development in asymmetric synthesis.
    Physical Properties

    Melting Point: 130-135 °C(lit.)

    Boiling Point: 500.263 °C at 760 mmHg

    Flash Point: 256.35 °C

    Density: 1.223 g/cm3

    Refractivity: -46 ° (C=2, EtOH)

    mg g kg ml l t