5-Bromo-2-chlorobenzoic acid, CAS No. 21739-92-4

Welcome to iChemical.com!

In the below part, please select the country you want us to ship to: Please note that once you've selected a shipping country, all pricing information on our website will be automatically updated to include door-to-door shipping to the country you specified.

North America

South America

Africa

Europe

Asia

Oceania

21739-92-4

Catalog No. EBD25508

CAS 21739-92-4

Name 5-Bromo-2-chlorobenzoic acid

Get Quote

Basic Information

Synonyms: 5-Bromo-2-chlorobenzoicacid Benzoicacid,5-bromo-2-chloro- BCBA 2-chloropyridine-4-carbonitrile 5-bromo-2-chlorobenzoate 2-Chloro-5-bromobenzoicacid 5-Bromo-2-chloro-benzoicacid

Molecular Formula: C7H4BrClO2

Molecular Weight: 235.46

MDL Number: MFCD00002415

Categories: Synthetic Chemistry > Organic Building Blocks > Halogenated Compounds Synthetic Chemistry > Organic Building Blocks > Carboxylic Acids and Esters Medicinal Chemistry > Pharmaceutical Intermediates > Drug Synthesis Building Blocks

Product Description:

5-Bromo-2-chlorobenzoic acid is a bifunctional aromatic building block featuring a carboxylic acid group, a bromine atom, and a chlorine atom on a benzene ring. Its molecular formula is C7H4BrClO2, and it serves as a key intermediate in organic synthesis. This compound is primarily utilized as a small molecule drug fragment in pharmaceutical research and development. The presence of both bromine and chlorine allows for selective cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig), while the carboxylic acid group enables further derivatization into amides, esters, or acid chlorides. It is commonly employed in the synthesis of biologically active molecules, including potential kinase inhibitors and other therapeutic agents. As a versatile synthetic building block, it is also widely used in general organic synthesis for constructing complex molecular architectures. Its dual halogenation pattern makes it particularly valuable for sequential functionalization in medicinal chemistry and materials science applications.

Physical Properties

Melting Point: 154-156 °C(lit.)

Boiling Point: 324.5 °C at 760 mmHg

Flash Point: 150.1 °C

Density: 1.809 g/cm3