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    21736-83-4

    Catalog No. EBD37323

    CAS 21736-83-4

    Name (+)-spectinomycin dihydrochloride

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    Basic Information

    Synonyms: SpectinomycinHydrochloride 4H-Pyrano(2,3-b)(1,4)benzodioxin-4-one,decahydro-4a,7,9-trihydroxy-2-methyl-6,8-bis(methylamino)- 4a,7,9-trihydroxy-2-methyl-6,8-bis(methylamino)decahydro-4H-pyrano[2,3-b][1,4]benzodioxin-4-one Spectinomycindihydrochloride SpectinomycinHCl (+)-spectinomycindihydrochloride

    Molecular Formula: C14H26Cl2N2O7

    Molecular Weight: 405.27

    Categories: Medicinal Chemistry > APIs and Their Salts > Anti-infectives Medicinal Chemistry > Biochemicals and Life Science Reagents > Saccharides, Nucleosides, and Nucleotides

    Product Description:
    (+)-Spectinomycin dihydrochloride is the dihydrochloride salt of spectinomycin, an aminocyclitol antibiotic produced by *Streptomyces spectabilis*. It is a white to off-white crystalline powder, highly soluble in water. Structurally, it is a tricyclic aminoglycoside-like compound, but it functions differently from typical aminoglycosides. Its primary and most significant application is as an active pharmaceutical ingredient (API) for the treatment of bacterial infections. It is particularly effective against *Neisseria gonorrhoeae* and is a key drug for treating uncomplicated gonorrhea, especially in cases of penicillin or tetracycline resistance. It works by binding to the 30S ribosomal subunit, inhibiting bacterial protein synthesis. It is also used in veterinary medicine for treating respiratory and enteric infections in animals. As a complex natural product derivative, it is not a general-purpose synthetic building block. Its classification is firmly rooted in its therapeutic use as an antibiotic, placing it directly within the API category for anti-infective drugs. Its structural relationship to sugar-based antibiotics also supports its secondary classification under biological chemicals.
    Physical Properties

    Melting Point: 194 °C

    Boiling Point: 583.1 °C at 760 mmHg

    Flash Point: 306.4 °C

    Solubility: water: 50 mg/mL, clear, faintly yellow

    Analytical Data

    Appearance: white powder

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