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    216854-23-8

    Catalog No. EBD2199052

    CAS 216854-23-8

    Name (S)-3-Boc-Aminopiperidine

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    Basic Information

    Synonyms: (S)-3-Boc-Aminopiperidine (S)-3-(Boc-amino)piperidine tert-butyl(3S)-piperidin-3-ylcarbamate (S)-3-N-Boc-aminopiperidine tert-butylN-[(3S)-piperidin-3-yl]carbamate

    Molecular Formula: C10H20N2O2

    Molecular Weight: 200.28

    MDL Number: MFCD03093383

    Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Heterocyclic Intermediates Synthetic Chemistry > Organic Building Blocks > Amines

    Product Description:
    (S)-3-(Boc-amino)piperidine is a chiral piperidine derivative featuring a Boc-protected amino group at the 3-position. It is a versatile and widely used building block in organic synthesis, particularly in medicinal chemistry. The Boc group serves as a common protecting group for amines, allowing for selective deprotection under mild acidic conditions. This compound is primarily employed as a key chiral intermediate in the synthesis of various pharmaceutical agents. Its piperidine scaffold is a privileged structure found in numerous bioactive molecules. The protected amine functionality enables its incorporation into target molecules through standard amide coupling or other transformations, facilitating the construction of complex drug candidates. As a high-purity chiral synthon, it is crucial for the development of enantiomerically pure compounds. It is commonly utilized in the research and production of potential drugs targeting the central nervous system, as well as other therapeutic areas. Its stability and commercial availability make it a standard reagent in many synthetic laboratories.
    Physical Properties

    Melting Point: 122-127°C

    Boiling Point: 304.8 °C at 760 mmHg

    Flash Point: 138.2 °C

    Density: 1.02 g/cm3

    mg g kg ml l t