2-chloro-5-(hydroxymethyl)pyridine, CAS No. 21543-49-7

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21543-49-7

Catalog No. EBD217271

CAS 21543-49-7

Name 2-chloro-5-(hydroxymethyl)pyridine

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Basic Information

Synonyms: 2-Chloro-5-hydroxymethylpyridine (6-chloropyridin-3-yl)methanol 2-chloro-5-hydroxymetyl-pyridine (6-chloro-3-pyridinyl)-methanol 6-chloro-3-pyridinecarbinol 6-chloro-3-pyridinemethanol CPCH2OH

Molecular Formula: C6H6ClNO

Molecular Weight: 143.57

MDL Number: MFCD01075226

Categories: Synthetic Chemistry > Organic Building Blocks > Halogenated Compounds Synthetic Chemistry > Organic Building Blocks > Phenols and Ethers Medicinal Chemistry > Pharmaceutical Intermediates > Heterocyclic Intermediates

Product Description:

2-Chloro-5-(hydroxymethyl)pyridine is a heterocyclic building block featuring a pyridine ring substituted with a chlorine atom at the 2-position and a hydroxymethyl group at the 5-position. This compound is primarily utilized as a key intermediate in the synthesis of pharmaceuticals, particularly in the development of bioactive molecules targeting neurological and inflammatory pathways. Its chloropyridine core allows for further functionalization via cross-coupling reactions, while the hydroxymethyl group serves as a handle for esterification or ether formation. Additionally, it is employed as a versatile synthetic building block in organic chemistry for constructing more complex heterocyclic structures.

Physical Properties

Melting Point: 51-54 °C(lit.)

Boiling Point: 120°C 0,4mm

Flash Point: >230 °F

Density: 1.324 g/cm3