(S)-2-Amino-3-(1-methyl-1H-indol-3-yl)propanoic acid, CAS No. 21339-55-9

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21339-55-9

Catalog No. EBD2223301

CAS 21339-55-9

Name (S)-2-Amino-3-(1-methyl-1H-indol-3-yl)propanoic acid

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Basic Information

Synonyms: (S)-2-Amino-3-(1-methyl-1H-indol-3-yl)propanoicacid L-Tryptophan,1-methyl- 1-Methyltryptophan L-(-)-1-Methyltryptophan L-1-Methyltryptophan DL-1-Methyltryptophan

Molecular Formula: C12H14N2O2

Molecular Weight: 218.25

MDL Number: MFCD00467133

Categories: Medicinal Chemistry > Biochemicals and Life Science Reagents > Phytochemicals and Natural Products Medicinal Chemistry > APIs and Their Salts > Nervous System Drugs

Product Description:

Abrine, also known as N-methyl-L-tryptophan, is a non-proteinogenic amino acid and a natural product. It is a structural analog of L-tryptophan and a known metabolite of the neurotoxin L-α-amino-β-methylaminopropionic acid (BMAA). Abrine is primarily found in the seeds of *Abrus precatorius* (rosary pea). Its primary significance lies in biomedical research. Abrine is used as a biochemical tool to study amino acid transport and metabolism, particularly in the context of neurological disorders. It has been investigated for its potential neurotoxic effects and its role as a biomarker. Historically, it has also been used as a toxicological marker. As a plant-derived alkaloid with specific biological activity, it is categorized as a natural product of interest for pharmacological and toxicological studies, fitting within the realm of life science reagents and investigational neurological agents.

Physical Properties

Melting Point: 242-245 °C(lit.)

Boiling Point: 429.3 °C at 760 mmHg

Flash Point: 213.4 °C

Density: 1.284 g/cm3