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    213388-72-8

    Catalog No. EBD3024111

    CAS 213388-72-8

    Name tert-butyl ((3S,4S)-4-fluoropyrrolidin-3-yl)carbamate

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    Basic Information

    Synonyms: N-[(3S,4S)-4-Fluoro-pyrrolidin-3-yl]carbamicacidtert-butylester tert-butyl((3S,4S)-4-fluoropyrrolidin-3-yl)carbamate Carbamicacid,N-[(3S,4S)-4-fluoro-3-pyrrolidinyl]-,1,1-dimethylethylester Carbamicacid,[(3S,4S)-4-fluoro-3-pyrrolidinyl]-,1,1-dimethylethylester(9CI)

    Molecular Formula: C9H17FN2O2

    Molecular Weight: 204.24

    Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Heterocyclic Intermediates Medicinal Chemistry > Pharmaceutical Intermediates > Chiral Intermediates

    Product Description:
    Tert-Butyl ((3S,4S)-4-fluoropyrrolidin-3-yl)carbamate is a chiral fluorinated pyrrolidine derivative. It serves as a key synthetic intermediate in pharmaceutical research and development. The molecule features a protected amine group (Boc) and a fluorine atom on a stereochemically defined pyrrolidine ring, making it a valuable chiral building block. This compound is primarily utilized in the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting the central nervous system. Its fluorinated pyrrolidine scaffold is a privileged structure found in several drug candidates and approved medicines, where it can influence pharmacokinetic properties such as metabolic stability and membrane permeability. The specific (3S,4S) stereochemistry is often critical for biological activity. As a high-value chiral intermediate, it is typically supplied for research and process development purposes. Handling requires standard precautions for laboratory chemicals, and its use is governed by the specific synthetic route and target molecule in medicinal chemistry programs.
    Physical Properties
    mg g kg ml l t