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    209963-04-2

    Catalog No. EBD3322366

    CAS 209963-04-2

    Name (2R)-2-AMINO-2-(3-BROMOPHENYL)ETHAN-1-OL

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    Basic Information

    Synonyms: (2R)-2-AMINO-2-(3-BROMOPHENYL)ETHAN-1-OL Benzeneethanol,β-amino-3-bromo-,(βR)-

    Molecular Formula: C8H10BrNO

    Molecular Weight: 216.08

    Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Chiral Intermediates Synthetic Chemistry > Organic Building Blocks > Amines

    Product Description:
    (R)-2-Amino-2-(3-bromophenyl)ethanol, with CAS number 209963-04-2, is a chiral amino alcohol derivative featuring a 3-bromophenyl substituent. This compound serves as a crucial chiral building block in pharmaceutical synthesis. Its structure combines a primary amine and a primary alcohol functional group, making it a versatile intermediate for constructing more complex molecules. The primary application of this compound is as a key chiral intermediate in the synthesis of active pharmaceutical ingredients (APIs). It is notably used in the preparation of adrenergic receptor agonists and other bioactive molecules where the (R)-configuration is essential for biological activity. The bromine atom on the phenyl ring provides a handle for further functionalization via cross-coupling reactions, such as Suzuki or Buchwald-Hartwig couplings, allowing for the introduction of diverse substituents. As a chiral synthon, it is valuable for introducing stereochemistry into target drug molecules. Handling requires standard precautions for amino alcohols and bromoarenes, including the use of personal protective equipment.
    Physical Properties
    mg g kg ml l t