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    209860-88-8

    Catalog No. EBD304468

    CAS 209860-88-8

    Name AFP-172

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    Basic Information

    Synonyms: Tafluprost free acid 16-phenoxy-15-deoxy-15,15-difluoro-17,18,19,20-tetranor-prostaglandinF2± AFP-172 tafluprostacid

    Molecular Formula: C22H28F2O5

    Molecular Weight: 410.45

    Categories: Medicinal Chemistry > APIs and Their Salts > Sensory Drugs

    Product Description:
    Tafluprost acid is the active pharmaceutical ingredient (API) and free acid form of the prostaglandin analog tafluprost. It is a synthetic prostaglandin F2α analog, structurally characterized by the presence of a fluoro substituent at the 15-position of the prostaglandin backbone, which enhances its stability and pharmacological profile. Its primary and well-defined application is in ophthalmology for the treatment of glaucoma and ocular hypertension. As the active metabolite of the prodrug tafluprost (marketed as a preservative-free formulation, e.g., Saflutan®), it functions by increasing the outflow of aqueous humor through the uveoscleral pathway, thereby effectively lowering intraocular pressure. It is a key therapeutic agent for managing conditions that can lead to optic nerve damage and vision loss. This compound is specifically developed and utilized as a high-purity active pharmaceutical substance. Its synthesis and quality control are strictly governed by pharmaceutical manufacturing standards to ensure safety and efficacy in final medicinal products.
    Physical Properties

    Storage: −20°C

    mg g kg ml l t