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    204326-24-9

    Catalog No. EBD2293831

    CAS 204326-24-9

    Name Azepino[3,2,1-hi]indole-2-carboxylicacid,1,2,4,5,6,7-hexahydro-5-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]-4-oxo-,(2S,9S)-(9CI)

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    Basic Information

    Synonyms: Azepino[3,2,1-hi]indole-2-carboxylicacid,5-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]-1,2,4,5,6,7-hexahydro-4-oxo-,(2S,5S)- Azepino[3,2,1-hi]indole-2-carboxylicacid,1,2,4,5,6,7-hexahydro-5-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]-4-oxo-,(2S,9S)-(9CI) Azepino[3,2,1-hi]indole-2-carboxylicacid,1,2,4,5,6,7-hexahydro-5-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]-4-oxo-,(2S-cis)-

    Molecular Formula: C28H24N2O5

    Molecular Weight: 468.5

    Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Heterocyclic Intermediates Medicinal Chemistry > Biochemicals and Life Science Reagents > Peptides and Peptidomimetics

    Product Description:
    This compound, (3S,6S)-3-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-4-oxo-1,2,3,4,6,7-hexahydroazacycloheptane[3,2,1-hi]indole-6-carboxylic acid, is a complex heterocyclic molecule featuring a fused azacycloheptane-indole core structure. It contains an Fmoc-protected amino group and a carboxylic acid functional group, making it a protected amino acid derivative. The primary application of this compound is as a specialized building block in peptide and peptidomimetic chemistry. Its unique, conformationally constrained bicyclic scaffold is designed to mimic specific secondary structures of peptides, potentially enhancing metabolic stability, receptor selectivity, and bioavailability. It is used in the research and development of novel therapeutic agents, particularly in the synthesis of peptide-based drugs or probes targeting various biological pathways. As a highly functionalized and chiral synthetic intermediate, it is not a commodity chemical but a research-grade product supplied for advanced medicinal chemistry and chemical biology studies. Its synthesis and use require expertise in solid-phase peptide synthesis (SPPS) or solution-phase coupling techniques.
    Physical Properties
    mg g kg ml l t