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    203395-59-9

    Catalog No. EBD347998

    CAS 203395-59-9

    Name 7-(4-bromobutoxy)-quinolin-2(1H)-one

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    Basic Information

    Synonyms: 7-(4-bromobutoxy)-quinolin-2(1H)-one 7-(4-bromobutoxy)quinolin-2(1H)-one

    Molecular Formula: C13H14BrNO2

    Molecular Weight: 296.16

    Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Heterocyclic Intermediates Synthetic Chemistry > Organic Building Blocks > Halogenated Compounds

    Product Description:
    7-(4-Bromobutoxy)-quinolin-2(1H)-one is a brominated quinolinone derivative. It serves as a crucial synthetic intermediate in medicinal chemistry, particularly for the development of kinase inhibitors. The molecule features a quinolin-2-one core, a privileged scaffold in drug discovery, functionalized with a flexible 4-bromobutoxy side chain at the 7-position. This compound is primarily utilized as a key building block in the synthesis of more complex, biologically active molecules. Its bromoalkoxy chain acts as a versatile handle for further chemical modifications, such as nucleophilic substitution reactions, allowing for the introduction of various amine or other functional groups to create targeted drug candidates. Research indicates its specific use in the synthesis pathway of potent and selective inhibitors targeting protein kinases like c-Met and ALK, which are important targets in oncology. As a bifunctional molecule containing both a heterocyclic core and a reactive alkyl halide moiety, it is a valuable reagent in organic synthesis. It is commercially available from suppliers specializing in pharmaceutical intermediates and advanced synthetic building blocks for research and development purposes.
    Physical Properties
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