Welcome to iChemical.com!

In the below part, please select the country you want us to ship to: Please note that once you've selected a shipping country, all pricing information on our website will be automatically updated to include door-to-door shipping to the country you specified.

    OK
    Get Quote Login
    20151-40-0

    Catalog No. EBD2016

    CAS 20151-40-0

    Name 2,4-Dibromoquinoline

    Get Quote
    Basic Information

    Synonyms: N-(4-Chloro-2-methyl-phenyl)-3-oxo-butanamide 2,4-Dibromoquinoline quinoline,2,4-dibromo-

    Molecular Formula: C9H5Br2N

    Molecular Weight: 286.95

    Categories: Synthetic Chemistry > Organic Building Blocks > Halogenated Compounds Medicinal Chemistry > Pharmaceutical Intermediates > Heterocyclic Intermediates

    Product Description:
    2,4-Dibromoquinoline is a halogenated heterocyclic compound featuring a quinoline core substituted with bromine atoms at the 2- and 4-positions. It serves as a versatile and valuable synthetic building block in organic chemistry. The presence of two bromine atoms at electronically distinct positions makes it a key intermediate for selective functionalization via cross-coupling reactions, such as Suzuki, Stille, or Buchwald-Hartwig couplings. Its primary application lies in medicinal chemistry and pharmaceutical research, where it is used as a crucial intermediate for the synthesis of more complex quinoline derivatives. These derivatives are often explored for their biological activities, including potential applications as kinase inhibitors, antimicrobial agents, or other pharmacologically active compounds. The molecule is a common starting point for constructing libraries of drug-like molecules. As a solid, it requires careful handling under standard laboratory safety protocols. It is typically stored in a cool, dry place, protected from light. Due to its role as a foundational scaffold, it is commercially available from suppliers specializing in fine chemicals and advanced intermediates for research and development.
    Physical Properties

    Melting Point: 92-94 °C

    Boiling Point: 344.3 °C at 760 mmHg

    Flash Point: 162 °C

    Density: 1.923 g/cm3</sup

    Safety Information

    Packing Level: III

    Hazard Category: 6.1

    Transport Codes: 2811

    mg g kg ml l t