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    20146-59-2

    Catalog No. EBD14144

    CAS 20146-59-2

    Name 4-Chloroquinolin-2(1H)-one

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    Basic Information

    Synonyms: 4-chloroquinolin-2(1H)-one 2-quinolinol,4-chloro- 4-Chloro-2-hydroxyquinoline 4-Chloroquinolin-2-ol

    Molecular Formula: C9H6ClNO

    Molecular Weight: 179.6

    Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Heterocyclic Intermediates

    Product Description:
    4-Chloro-2-hydroxyquinoline is a heterocyclic organic compound featuring a quinoline core substituted with a chlorine atom at the 4-position and a hydroxyl group at the 2-position. It serves as a versatile and important synthetic intermediate in medicinal chemistry. Its primary application is as a key building block for the synthesis of various biologically active molecules, particularly in the development of pharmaceutical agents. The presence of both reactive sites (chloro and hydroxyl groups) allows for diverse chemical modifications, enabling its use in constructing complex drug candidates. It is notably utilized in the synthesis of compounds with potential antibacterial, antifungal, and anticancer activities. As a halogenated hydroxyquinoline derivative, it is a fundamental scaffold in heterocyclic chemistry. Its utility extends beyond specific drug synthesis to serve as a general-purpose precursor for creating libraries of quinoline-based compounds in drug discovery research.
    Physical Properties

    Boiling Point: 366.9 °C at 760 mmHg

    Flash Point: 175.7 °C

    Density: 1.38 g/cm3

    mg g kg ml l t