(2S)-N-[(2S)-1-[(2-amino-2-oxoethyl)amino]-4-methyl-1-oxopentan-2-yl]pyrrolidine-2-carboxamide, CAS No. 2002-44-0

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2002-44-0

Catalog No. EBD97498

CAS 2002-44-0

Name (2S)-N-[(2S)-1-[(2-amino-2-oxoethyl)amino]-4-methyl-1-oxopentan-2-yl]pyrrolidine-2-carboxamide

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Basic Information

Synonyms: (2S)-N-[(1S)-1-[(2-amino-2-oxo-ethyl)carbamoyl]-3-methyl-butyl]pyrrolidine-2-carboxamide (2S)-N-[(2S)-1-[(2-amino-2-oxoethyl)amino]-4-methyl-1-oxopentan-2-yl]pyrrolidine-2-carboxamide Melanocyte-StimulatingHormone-ReleaseInhibitingFactor H-Pro-Leu-Gly-NH2 L-Prolyl-L-leucylglycinamide,hemihydrate L-prolyl-L-leucylglycinamide msh-releaseinhibitingfactor mshreleaseinhibitingfactor,amide mif-1 mif,amide mif-i pro-leu-glyamide pro-leu-gly-nh2 plg-nh2

Molecular Formula: C13H24N4O3

Molecular Weight: 284.35

Categories: Medicinal Chemistry > Biochemicals and Life Science Reagents > Peptides and Peptidomimetics Medicinal Chemistry > APIs and Their Salts > Nervous System Drugs

Product Description:

This compound, known as Melanocyte-Stimulating Hormone Release-Inhibiting Factor (MIF) or Pro-Leu-Gly-NH2, is a synthetic tripeptide amide with the sequence Proline-Leucine-Glycinamide. It is a structural analog of the C-terminal tripeptide of oxytocin and functions as a neuropeptide. Its CAS number is 2002-44-0. MIF acts as an inhibitor of melanocyte-stimulating hormone (MSH) release and has been extensively studied for its central nervous system (CNS) effects. Research indicates it possesses significant neuropharmacological properties, including potential antiparkinsonian activity by modulating dopamine receptor sensitivity. It has been investigated as a potential therapeutic agent for Parkinson's disease and other neurological disorders. While primarily a research tool in neuroscience and endocrinology, its status as a defined neuroactive peptide places it within the realm of investigational pharmaceutical agents targeting the central nervous system. It is used in biochemical and pharmacological research to study peptide hormone regulation and dopaminergic pathways.

Physical Properties

Boiling Point: 626.2 °C at 760 mmHg

Flash Point: 332.5 °C

Density: 1.147 g/cm3