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    2002-29-1

    Catalog No. EBD12235

    CAS 2002-29-1

    Name Flumethasone 21-pivalate

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    Basic Information

    Synonyms: flumetasone21-pivalate 6,9-difluoro-11,17-dihydroxy-16-methyl-3,20-dioxopregna-1,4-dien-21-yl2,2-dimethylpropanoate (6alpha,8xi,10xi,11beta,13xi,16alpha)-6,9-difluoro-11,17-dihydroxy-16-methyl-3,20-dioxopregna-1,4-dien-21-yl2,2-dimethylpropanoate (6alpha,11beta,16alpha)-6,9-difluoro-11,17-dihydroxy-16-methyl-3,20-dioxopregna-1,4-dien-21-yl2,2-dimethylpropanoate (6alpha,8xi,11beta,14xi,16alpha)-6,9-difluoro-11,17-dihydroxy-16-methyl-3,20-dioxopregna-1,4-dien-21-yl2,2-dimethylpropanoate flumethasonepivalate 21-pivalate locacorten locorten pregna-1,4-diene-3,20-dione,6-alpha,9-difluoro-11-beta,17,21-trihydroxy-16-alp 6a,9a-Difluoro-16a-methyl-prednisolone-21-pivalate Flumethasone21-pivalate (6alpha,11beta,16alpha)-6,9-difluoro-11,17-dih

    Molecular Formula: C27H36F2O6

    Molecular Weight: 494.57

    Categories: Medicinal Chemistry > APIs and Their Salts > Dermatological Drugs Medicinal Chemistry > APIs and Their Salts > Immuno-modulators and Anti-inflammatory Drugs

    Product Description:
    Flumetasone pivalate is a synthetic corticosteroid ester, specifically the 21-pivalate ester of flumetasone. It is a potent glucocorticoid receptor agonist. Its primary application is in dermatology as a topical corticosteroid for the treatment of various inflammatory skin conditions such as eczema, psoriasis, and dermatitis. It functions by exerting potent anti-inflammatory, antipruritic (anti-itch), and vasoconstrictive effects, helping to reduce redness, swelling, and itching. It is commonly formulated in creams, ointments, and lotions for external use. As a specific active pharmaceutical ingredient (API), it is not a general-purpose synthetic building block. Its use is highly specialized within the pharmaceutical field for targeted therapeutic action.
    Physical Properties

    Boiling Point: 600.3 °C at 760 mmHg

    Flash Point: 316.8 °C

    Density: 1.27 g/cm3

    mg g kg ml l t