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    200125-70-8

    Catalog No. EBD4017195

    CAS 200125-70-8

    Name (2S)-1,2,3,4-tetrahydro-2-methyl-Quinoline

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    Basic Information

    Synonyms: (S)-2-甲基-1,2,3,4-四氢喹啉 (S)-2-甲基-1,2,3,4-四氢喹啉

    Molecular Formula: C10H13N

    Molecular Weight: 147.22

    Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Heterocyclic Intermediates Synthetic Chemistry > Organic Building Blocks > Amines

    Product Description:
    (S)-2-Methyl-1,2,3,4-tetrahydroquinoline is a chiral, saturated heterocyclic compound featuring a tetrahydroquinoline core with a methyl substituent at the 2-position. It is a versatile chiral building block and intermediate in organic synthesis. This compound is primarily utilized in the pharmaceutical industry as a key chiral intermediate. Its tetrahydroquinoline scaffold is a privileged structure found in numerous bioactive molecules. For instance, it serves as a crucial precursor in the synthesis of (S)-(-)-Nornicotine, a metabolite of nicotine with research applications in neuroscience. The chiral center at the 2-position makes it valuable for constructing enantiomerically pure compounds, particularly in the development of potential drugs targeting the central nervous system and other therapeutic areas. As a secondary amine, it can act as a ligand or a base in certain catalytic reactions. Its primary commercial and research significance lies in its role as a specialized, chirally-defined synthetic intermediate rather than as a bulk commodity chemical or a reagent with broad, non-specific utility.
    Physical Properties
    mg g kg ml l t