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    19932-85-5

    Catalog No. EBD44360

    CAS 19932-85-5

    Name 6-Bromo-2-benzoxazolinone

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    Basic Information

    Synonyms: 6-BROMO-BENZOXAZOLINONE 6-BROMO-2(3H)-BENZOXAZOLONE 6-BROMOBENZOXAZOLINE 6-Bromo-2-benzoxazolinone 6-bromo-1,3-benzoxazol-2(3H)-one

    Molecular Formula: C7H4BrNO2

    Molecular Weight: 214.02

    MDL Number: MFCD00694727

    Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Heterocyclic Intermediates Synthetic Chemistry > Organic Building Blocks > Halogenated Compounds

    Product Description:
    6-Bromobenzoxazolone is a heterocyclic organic compound featuring a benzoxazolone core substituted with a bromine atom at the 6-position. It serves as a versatile and valuable building block in medicinal chemistry and organic synthesis. Its primary application is as a key intermediate in the synthesis of various pharmacologically active molecules. The bromine atom provides a reactive site for further functionalization via cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig), allowing for the introduction of diverse substituents. This scaffold is commonly utilized in the development of compounds targeting central nervous system disorders, such as GABA-A receptor modulators and potential anxiolytic agents. As a bifunctional synthon containing both a reactive halogen and a heterocyclic pharmacophore, it is widely employed in the construction of drug-like libraries and the exploration of structure-activity relationships. Its utility extends to materials science research where similar heterocyclic structures are of interest.
    Physical Properties

    Melting Point: 192-196 °C

    Density: 1.809 g/cm3

    mg g kg ml l t