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    19898-39-6

    Catalog No. EBD200557

    CAS 19898-39-6

    Name benzyl N-[1-amino-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]carbamate

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    Basic Information

    Synonyms: benzylN-[2-amino-1-[(4-hydroxyphenyl)methyl]-2-oxo-ethyl]carbamate benzylN-[1-amino-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]carbamate Z-Tyr-NH2 Z-L-tyrosineamide Nalpha-[(benzyloxy)carbonyl]tyrosinamide

    Molecular Formula: C17H18N2O4

    Molecular Weight: 314.34

    Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Chiral Intermediates Medicinal Chemistry > Biochemicals and Life Science Reagents > Peptides and Peptidomimetics

    Product Description:
    Benzyl N-[1-amino-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]carbamate is a chiral amino acid derivative, specifically a protected form of L-tyrosine amide. Its molecular structure features a tyrosine-like backbone with a benzyloxycarbonyl (Cbz) protecting group on the amine and a primary amide at the C-terminus. This compound is a white to off-white crystalline powder. This chemical serves as a crucial chiral building block in the synthesis of peptides and peptidomimetics. The Cbz group is a common amine protecting group in peptide chemistry, and the presence of the 4-hydroxyphenyl (tyrosyl) side chain makes it a key intermediate for incorporating tyrosine residues or their analogs into target sequences. It is particularly valuable in the research and development of bioactive peptides, peptide hormones, and potential therapeutic agents where the specific stereochemistry and functionality of tyrosine are required. As a specialized synthetic intermediate, its primary application is confined to laboratory-scale organic synthesis and pharmaceutical research. It is not a commodity chemical and is typically handled under controlled conditions by trained personnel, following standard safety protocols for fine chemicals.
    Physical Properties

    Boiling Point: 610.2°Cat760mmHg

    Flash Point: 322.8°C

    Density: 1.286g/cm3

    mg g kg ml l t