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    19840-99-4

    Catalog No. EBD52410

    CAS 19840-99-4

    Name 7-Amino-4-methylquinolin-2(1H)-one

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    Basic Information

    Synonyms: carbostyril124 7-Amino-4-methyl-2-quinolinone 2(1H)-Quinolinone,7-amino-4-methyl- 7-amino-4-methylquinolin-2(1H)-one

    Molecular Formula: C10H10N2O

    Molecular Weight: 174.2

    MDL Number: MFCD00134256

    Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Heterocyclic Intermediates Medicinal Chemistry > Biochemicals and Life Science Reagents > Fluorescent Probes and Labeling Reagents

    Product Description:
    7-Amino-4-methylquinolin-2(1H)-one, also known as Quinolin-124, is a heterocyclic organic compound featuring a quinolinone core structure substituted with an amino group at the 7-position and a methyl group at the 4-position. This compound serves as a crucial intermediate in the synthesis of various biologically active molecules, particularly within the pharmaceutical sector. Its primary and most significant application is as a key precursor in the synthesis of quinolone-based antibiotics, such as ciprofloxacin and norfloxacin. The 7-amino group is a critical site for structural modification to introduce different piperazinyl or other amine substituents, which directly influence the antibacterial spectrum and potency of the final drug. Beyond its role as a pharmaceutical intermediate, this compound and its derivatives have been explored as fluorescent probes and markers in biochemical research due to their inherent photophysical properties. As a versatile heterocyclic building block, it finds utility in medicinal chemistry for constructing libraries of compounds with potential therapeutic activities. Handling requires standard laboratory precautions for organic compounds, including the use of personal protective equipment due to its potential irritant properties.
    Physical Properties

    Melting Point: 278-280 °C(lit.)

    Boiling Point: 417.6 °C at 760 mmHg

    Flash Point: 206.4 °C

    Density: 1.223 g/cm3

    Analytical Data

    Appearance: off-white to tan solid

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