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    19798-81-3

    Catalog No. EBD473020

    CAS 19798-81-3

    Name 2-Amino-6-bromopyridine

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    Basic Information

    Synonyms: 2-Amino-6-bromopyridine 6-bromo-2-pyridinamine 6-bromopyridin-2-amine 2-amino-6-bromopyridinium Aminobromopyridine

    Molecular Formula: C5H5BrN2

    Molecular Weight: 173.01

    MDL Number: MFCD00137843

    Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Heterocyclic Intermediates Synthetic Chemistry > Organic Building Blocks > Amines

    Product Description:
    2-Amino-6-bromopyridine is an organic compound featuring a pyridine ring substituted with an amino group at the 2-position and a bromine atom at the 6-position. It is a white to off-white crystalline powder. This compound serves as a versatile and important heterocyclic building block in organic synthesis. Its primary application is as a key intermediate in the pharmaceutical industry. The presence of both an amino group and a bromine atom on the pyridine ring makes it a valuable precursor for constructing more complex molecules through various coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic substitution reactions. It is specifically used in the synthesis of various drug candidates and active pharmaceutical ingredients (APIs), particularly those containing fused or substituted pyridine motifs. As a bifunctional synthon, it is also widely utilized in academic and industrial research for the preparation of ligands, agrochemicals, and functional materials. Standard safety precautions for handling brominated and aminopyridine compounds should be observed.
    Physical Properties

    Melting Point: 88-91 °C(lit.)

    Boiling Point: 272.954 °C at 760 mmHg

    Flash Point: 118.879 °C

    Density: 1.71 g/cm3

    Analytical Data

    Appearance: Slightly yellow to light brown powder

    mg g kg ml l t