Galanthamine hydrobromide, CAS No. 1953-04-4

Welcome to iChemical.com!

In the below part, please select the country you want us to ship to: Please note that once you've selected a shipping country, all pricing information on our website will be automatically updated to include door-to-door shipping to the country you specified.

North America

South America

Africa

Europe

Asia

Oceania

1953-04-4

Catalog No. EBD46216

CAS 1953-04-4

Name Galanthamine hydrobromide

Get Quote

Basic Information

Synonyms: galanthaminehydrobromide galantaminehydrobromide GalantamineHbr galanthaminehydrobromide(1:1) (4aS,6R,8aS)-6-hydroxy-3-methoxy-11-methyl-5,6,9,10,11,12-hexahydro-4aH-[1]benzofuro[3a,3,2-ef][2]benzazepin-11-ium GalanthamineHBr 5a,6,7,8,8a,12b-hexahydrogalanthaminehydrobromide(1:1) N-(2-Mercaptopropionyl)glycine alpha-Mercaptopropionylglycine

Molecular Formula: C17H22BrNO3

Molecular Weight: 368.27

MDL Number: MFCD00067672

Categories: Medicinal Chemistry > APIs and Their Salts > Nervous System Drugs Medicinal Chemistry > Biochemicals and Life Science Reagents > Phytochemicals and Natural Products

Product Description:

Galantamine hydrobromide is a salt form of galantamine, a tertiary alkaloid originally isolated from plants of the *Galanthus* genus. It is a white to off-white crystalline powder. Chemically, it is a reversible and competitive acetylcholinesterase inhibitor. Its primary and well-established application is as an active pharmaceutical ingredient (API) for the treatment of mild to moderate Alzheimer's disease and other forms of dementia. It works by increasing the concentration of acetylcholine in the brain, thereby improving cholinergic neurotransmission. It is also noted for its allosteric modulation of nicotinic acetylcholine receptors. As a natural product derivative, it serves as a key reference standard in pharmacological research. The hydrobromide salt is the common form used in pharmaceutical formulations due to its stability and solubility properties.

Physical Properties

Melting Point: 256 °C

Boiling Point: 439.3 °C at 760 mmHg

Flash Point: 219.5 °C

Refractivity: -95 ° (C=1.4, H2O)

Storage: −20°C

Safety Information

Packing Level: III

Hazard Category: 6.1

Transport Codes: 1544PSN1

Analytical Data

Appearance: white to offf-white powder