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    195252-68-7

    Catalog No. EBD4017386

    CAS 195252-68-7

    Name (1R)-1-Cyclopropylethan-1-amine hydrochloride

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    Basic Information

    Molecular Formula: C5H12ClN

    Molecular Weight: 121.61

    Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Chiral Intermediates Synthetic Chemistry > Organic Building Blocks > Amines

    Product Description:
    (1R)-1-Cyclopropylethan-1-amine hydrochloride is a chiral amine salt, specifically the hydrochloride salt of (1R)-1-cyclopropylethylamine. It is a white to off-white crystalline powder. The compound features a cyclopropyl group attached to a chiral carbon bearing an amino group, making it a valuable chiral building block. This compound is primarily used as a key chiral intermediate in the pharmaceutical industry. It is notably employed in the synthesis of various active pharmaceutical ingredients (APIs). Its structural motif, combining a cyclopropyl ring with a chiral amine, is significant for imparting specific biological activity and metabolic stability to drug molecules. It serves as a crucial precursor in multi-step synthetic routes. As a chiral amine, it is also a versatile synthon in organic chemistry for constructing complex molecules. Handling requires standard precautions for amine hydrochlorides, including avoiding inhalation and contact with skin or eyes.
    Physical Properties
    mg g kg ml l t