4-bromopyridine hydrochloride, CAS No. 19524-06-2

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19524-06-2

Catalog No. EBD583215

CAS 19524-06-2

Name 4-bromopyridine hydrochloride

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Basic Information

Synonyms: 4-bromopyridinehydrochloride 4-bromopyridiniumchloride 4-BromopyridineHCL 4-bromopyridinehydrochloride(1:1) 2-(tert-butoxycarbonyl)-1,2,3,4-tetrahydroisoquinoline-5-carboxylicacid

Molecular Formula: C5H5BrClN

Molecular Weight: 194.46

MDL Number: MFCD00012828

Categories: Synthetic Chemistry > Organic Building Blocks > Halogenated Compounds Synthetic Chemistry > Organic Building Blocks > Amines

Product Description:

4-Bromopyridine hydrochloride is an organic salt consisting of a 4-bromopyridine molecule protonated with hydrochloric acid. It serves as a versatile and fundamental building block in organic synthesis. The presence of both a halogen (bromine) and a basic nitrogen atom (in the pyridine ring) makes it a bifunctional reagent. Its primary application is as a key intermediate in the synthesis of more complex heterocyclic compounds, particularly in pharmaceutical and agrochemical research. The bromine atom is amenable to various cross-coupling reactions (e.g., Suzuki, Stille, Negishi), while the pyridine nitrogen can act as a ligand or be further functionalized. It is commonly used to introduce the 4-pyridyl moiety into target molecules. This compound is typically handled as a solid and requires storage in a cool, dry place. Standard safety precautions for handling halogenated and basic organic compounds should be observed.

Physical Properties

Melting Point: 270 °C (dec.)(lit.)

Boiling Point: 185.2 °C at 760 mmHg

Flash Point: 65.8 °C

Density: 1.598 g/cm3

Analytical Data

Appearance: White crystalline powder