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    19141-39-0

    Catalog No. EBD15993

    CAS 19141-39-0

    Name (R)-1-Chloro-2-propanol

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    Basic Information

    Synonyms: 2-PROPANOL,1-CHLORO-,(2R)- (R)-1-CHLORO-2-PROPANOL98+% (2R)-1-Chloro-2-propanol (R)-1-Chloro-2-propanol

    Molecular Formula: C3H7ClO

    Molecular Weight: 94.54

    MDL Number: MFCD01862132

    Categories: Synthetic Chemistry > Organic Building Blocks > Halogenated Compounds Medicinal Chemistry > Pharmaceutical Intermediates > Chiral Intermediates

    Product Description:
    (R)-1-Chloro-2-propanol is a chiral organic compound with the molecular formula C3H7ClO. It is a colorless to pale yellow liquid and serves as a versatile chiral building block in organic synthesis. Its structure features both a chlorine atom and a hydroxyl group on adjacent carbon atoms, making it a bifunctional intermediate. This compound is primarily utilized as a key chiral precursor in the synthesis of various pharmaceuticals and fine chemicals. Its enantiopure form is particularly valuable for introducing chirality into target molecules. A notable application is its use in the synthesis of (R)-epichlorohydrin, which is a crucial intermediate for producing beta-blocker drugs like (R)-propranolol and other active pharmaceutical ingredients (APIs) that require specific stereochemistry. As a reactive halohydrin, (R)-1-chloro-2-propanol requires careful handling due to its potential toxicity, irritancy, and moisture sensitivity. It is commercially available from suppliers specializing in chiral intermediates and fine chemicals for research and development purposes.
    Physical Properties

    Boiling Point: 126.499 °C at 760 mmHg

    Flash Point: 54.541 °C

    Density: 1.083 g/cm3

    mg g kg ml l t