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    191109-51-0

    Catalog No. EBD3008856

    CAS 191109-51-0

    Name (S)-2-amino-2-(4-chlorophenyl)ethanol

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    Basic Information

    Synonyms: (betaS)-beta-Amino-4-chlorobenzeneethanol (S)-2-amino-2-(4-chlorophenyl)ethanol

    Molecular Formula: C8H10ClNO

    Molecular Weight: 171.62

    Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Chiral Intermediates Synthetic Chemistry > Organic Building Blocks > Amines

    Product Description:
    (S)-2-Amino-2-(4-chlorophenyl)ethanol is a chiral amino alcohol derivative featuring a 4-chlorophenyl group and a primary amino group. It serves as a crucial chiral building block in pharmaceutical synthesis. This compound is primarily utilized as a key intermediate in the production of chiral active pharmaceutical ingredients (APIs). Its structure, containing both a chiral center and a functionalized aromatic ring, makes it valuable for constructing molecules with specific stereochemistry required for biological activity. It is notably employed in the synthesis of certain β-adrenergic receptor antagonists and other therapeutic agents where the (S)-configuration is essential for efficacy. As a bifunctional chiral synthon, it is also used in asymmetric synthesis and catalysis research. Handling requires standard precautions for amino alcohols, including protection from moisture and air.
    Physical Properties

    Storage: −20°C

    mg g kg ml l t