(S)-Chroman-4-amine, CAS No. 188198-38-1

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188198-38-1

Catalog No. EBD2224114

CAS 188198-38-1

Name (S)-Chroman-4-amine

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Basic Information

Synonyms: (S)-Chroman-4-amine 2h-1-benzopyran-4-amine,3,4-dihydro-,(4s)-(9ci) (4s)-3,4-dihydro-2h-1-benzopyran-4-amine 2h-1-benzopyran-4-amine,3,4-dihydro-,(4s)- (s)-3,4-dihydro-2h-chromen-4-amine (4S)-3,4-Dihydro-2H-chromen-4-amin (4S)-Chroman-4-amine (4S)-3,4-dihydro-2H-chromen-4-amine

Molecular Formula: C9H11NO

Molecular Weight: 149.19

MDL Number: MFCD06761755

Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Heterocyclic Intermediates Synthetic Chemistry > Organic Building Blocks > Amines

Product Description:

(S)-Chroman-4-amine is a chiral amine compound featuring a benzodihydropyran (chroman) scaffold. It serves as a key chiral building block in pharmaceutical synthesis. The (S)-enantiomer is of particular interest due to its specific spatial configuration, which is crucial for imparting desired biological activity in final drug molecules. This compound is primarily utilized in the research and development of central nervous system (CNS) active drugs and other therapeutic agents. Its structure makes it a valuable intermediate for constructing molecules that interact with biological targets such as serotonin and dopamine receptors. It has been cited in patent literature related to the synthesis of potential antidepressants and neuroprotective agents. As a bifunctional synthon containing both an amine group and a chroman heterocycle, (S)-chroman-4-amine enables efficient modular synthesis. It is commercially available from suppliers specializing in fine chemicals and chiral intermediates for medicinal chemistry.

Physical Properties

Boiling Point: 237.4°C at 760 mmHg

Flash Point: 102.1°C

Density: 1.106g/cm3