OSELTAMIVIR ACID, CAS No. 187227-45-8

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187227-45-8

Catalog No. EBD3068697

CAS 187227-45-8

Name OSELTAMIVIR ACID

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Basic Information

Synonyms: Oseltamivir (acid) Oseltamivir Acid GS4071 1-Cyclohexene-1-carboxylicacid,4-(acetylamino)-5-amino-3-(1-ethylpropoxy)-,(3R,4R,5S)-OseltamivirCarboxylicAcid,4-(Acetylamino)-5-amino-3-(1-ethylpropoxy)-1-cyclohexence-1-carboxylicAcid GS-4071 AIDS095377 AIDS-095377 OSELTAMIVIRCARBOXYLATE OSELTAMIVIRCARBOXYLICACID 204255-11-8(MONOPHOSPATESALT) (3R,4R,5S)-4-ACETAMIDO-5-AMINO-3-(1-ETHYLPROPOXY)-1-CYCLOHEX-ENE-1-CARBOXYLICACID 1-CYCLOHEXENE-1-CARBOXYLICACID,4-(ACETYLAMINO)-5-AMINO-3-(1-ETHYLPROPOXY)-,(3R,4R,5S)- OSELTAMIVIRACID (3R,4R,5S)-4-(acetylamino)-5-amino-3-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylicacid

Molecular Formula: C14H24N2O4

Molecular Weight: 284.36

Categories: Medicinal Chemistry > APIs and Their Salts > Anti-infectives Medicinal Chemistry > Drug Impurities and Reference Standards > Impurity Standards

Product Description:

Oseltamivir acid, also known as oseltamivir carboxylate, is the pharmacologically active metabolite of the prodrug oseltamivir phosphate (Tamiflu®). It is a potent and selective inhibitor of influenza virus neuraminidase, an enzyme essential for the release of newly formed viral particles from infected cells. This inhibition effectively halts the spread of the virus within the respiratory tract. As the active form of the widely used antiviral drug, oseltamivir acid is the key substance responsible for the therapeutic effect against influenza A and B viruses. It is a critical reference standard and impurity in the quality control and pharmacokinetic studies of oseltamivir phosphate formulations. Its chemical structure features a cyclohexene ring with amino and pentyloxy substituents, and a carboxylic acid group that is esterified in the prodrug.

Physical Properties

Boiling Point: 508.7°Cat760mmHg

Flash Point: 261.5°C

Density: 1.15g/cm3