H-Cys-OMe·HCl, CAS No. 18598-63-5

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18598-63-5

Catalog No. EBD2198199

CAS 18598-63-5

Name H-Cys-OMe·HCl

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Basic Information

Synonyms: H-Cys-OMe·HCl L-Cysteinemethylesterhydrochloride H-Cys-OMe.HCl Methylcysteinehydrochloride Visclair methylcysteinatehydrochloride(1:1) (2R)-1-methoxy-1-oxo-3-sulfanylpropan-2-aminiumchloride (2S)-1-methoxy-1-oxo-3-sulfanylpropan-2-aminiumchloride

Molecular Formula: C4H10ClNO2S

Molecular Weight: 171.65

MDL Number: MFCD00038985

Categories: Medicinal Chemistry > Biochemicals and Life Science Reagents > Amino Acids and Derivatives Synthetic Chemistry > Organic Building Blocks > Amines

Product Description:

L-Cysteine methyl ester hydrochloride is a derivative of the amino acid L-cysteine, where the carboxylic acid group is esterified to a methyl ester and the amino group is in the form of a hydrochloride salt. This modification enhances its lipophilicity compared to free cysteine. Its primary application is in the field of peptide synthesis and biochemical research. The methyl ester protects the carboxyl group, allowing for selective reactions at the amino group. It serves as a crucial building block for introducing the L-cysteine residue into synthetic peptides and for preparing other cysteine derivatives. It is also used in the synthesis of various pharmaceuticals and as a precursor for compounds with antioxidant or chelating properties. This compound is hygroscopic and should be stored under inert conditions. It is a valuable chiral synthon in organic chemistry due to the presence of both a protected amine and a thiol group, which can be further functionalized.

Physical Properties

Melting Point: 142 °C (dec.)(lit.)

Boiling Point: 197.2 °C at 760 mmHg

Flash Point: 73.1 °C

Solubility: soluble in water

Refractivity: -2.5 ° (C=20, MeOH)

Storage: −20°C

Analytical Data

Appearance: white crystalline powder