2-Chlorobenzyl Alcohol, CAS No. 17849-38-6

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17849-38-6

Catalog No. EBD30710

CAS 17849-38-6

Name 2-Chlorobenzyl Alcohol

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Basic Information

Synonyms: 2-chloro-benzenemethanol 2-Chlorobenzylalcohol o-chlorobenzylalcohol

Molecular Formula: C7H7ClO

Molecular Weight: 142.58

MDL Number: MFCD00004604

Categories: Synthetic Chemistry > Organic Building Blocks > Halogenated Compounds Medicinal Chemistry > Pharmaceutical Intermediates > Other Pharmaceutical Intermediates

Product Description:

2-Chlorobenzyl alcohol is an organic compound featuring a benzene ring substituted with a chloromethyl group (-CH2Cl) and a hydroxyl group (-OH) at the ortho position. It is a colorless to pale yellow liquid or low-melting solid with a molecular formula of C7H7ClO. This compound serves as a versatile bifunctional building block in organic synthesis. The reactive chloromethyl and hydroxyl groups allow it to be used in various transformations, including etherification, esterification, and nucleophilic substitution reactions. Its primary industrial application is as a key intermediate in the synthesis of pharmaceuticals and agrochemicals. For instance, it is utilized in the production of certain benzodiazepine derivatives and other active pharmaceutical ingredients (APIs). As a halogenated alcohol, it requires careful handling due to potential skin and eye irritation. It is typically stored under inert conditions to prevent degradation.

Physical Properties

Melting Point: 69-71 °C(lit.)

Boiling Point: 227 °C(lit.)

Flash Point: 227°C

Density: 1.237 g/cm3

Solubility: Slightly soluble in water

Storage: Store at RT.

Analytical Data

Appearance: White fine crystalline powder