trans-4-(Boc-amino)cyclohexylamine, CAS No. 177906-48-8

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177906-48-8

Catalog No. EBD87866

CAS 177906-48-8

Name trans-4-(Boc-amino)cyclohexylamine

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Basic Information

Synonyms: trans-4-(Boc-amino)cyclohexylamine trans-4-[[(1,1-dimethylethoxy)carbonyl]amino]-cyclohexylamine (trans-4-aminocyclohexyl)carbamicacidtert-butylester trans-(4-aminocyclohexyl)carbamicacidtert-butylester trans-1-amino-4-tert-butoxycarbonylaminocyclohexane N-tert-butoxycarbonyl-trans-1,4-cyclohexanediamine trans-1-amino-4-t-butoxycarbonylamino-cyclohexane Trans-N-Boc-1,4-Cyclohexanediamine N-Boc-Trans-1,4-Cyclohexanediamine Tert-ButylTrans-4-Aminocyclohexylcarbamate Trans-(4-Amino-Cyclohexyl)-CarbamicAcidTert-ButylEster Trans-1-Boc-Amino-1,4-Cyclohexanediamine 1-N-Boc-Trans-1,4-Cyclohexyldiamine trans-1n-boc-cyclohexane-1,4-diamine trans-cyclohexane-1,4-diamine,n1-bocprotected

Molecular Formula: C11H22N2O2

Molecular Weight: 214.3

MDL Number: MFCD03001719

Categories: Synthetic Chemistry > Organic Building Blocks > Amines

Product Description:

Trans-4-(Boc-amino)cyclohexylamine is a chiral diamine building block featuring a tert-butoxycarbonyl (Boc) protected amino group at the 4-position of a trans-1,4-cyclohexane ring. The trans configuration provides a rigid, stereochemically defined scaffold, while the Boc group serves as a stable protecting group for the primary amine. This compound is primarily utilized as a key intermediate in the synthesis of pharmaceutical agents, particularly in the development of kinase inhibitors, receptor modulators, and other bioactive molecules where the trans-cyclohexane diamine motif is crucial for biological activity. It is also widely employed as a versatile synthetic building block in organic chemistry for constructing complex molecules, including chiral ligands and peptidomimetics. Its dual functionality allows for selective deprotection and further functionalization, making it a valuable tool in medicinal chemistry and drug discovery.

Physical Properties

Boiling Point: 322.073 °C at 760 mmHg

Flash Point: 148.585 °C

Density: 1.029 g/cm3