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    176970-12-0

    Catalog No. EBD36800

    CAS 176970-12-0

    Name (S)-3-benzyloxycarbonylaminopyrrolidine

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    Basic Information

    Synonyms: (S)-3-N-CBZ-AMINOPYRROLIDINE Benzyl(3S)-pyrrolidin-3-ylcarbamate Carbamicacid,N-[(3S)-3-pyrrolidinyl]-,phenylmethylester benzylN-[(3S)-pyrrolidin-3-yl]carbamate (S)-3-(Cbz-aMino)pyrrolidine (S)-3-(benzyloxycarbonylamino)pyrrolidine (S)-3-benzyloxycarbonylaminopyrrolidine (s)-benzylpyrrolidin-3-ylcarbamate carbamicacid,(3s)-3-pyrrolidinyl-,phenylmethylester(9ci)

    Molecular Formula: C12H16N2O2

    Molecular Weight: 220.27

    MDL Number: MFCD04115315

    Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Heterocyclic Intermediates Synthetic Chemistry > Organic Building Blocks > Amines

    Product Description:
    (S)-3-N-Cbz-aminopyrrolidine is a chiral pyrrolidine derivative featuring a Cbz-protected amino group at the 3-position. It is a white to off-white crystalline powder with the molecular formula C12H16N2O2. This compound serves as a versatile and crucial chiral building block in organic synthesis, particularly in the pharmaceutical industry. Its primary application is as a key intermediate in the synthesis of various biologically active molecules and active pharmaceutical ingredients (APIs). The chiral pyrrolidine scaffold is a privileged structure found in numerous drugs, especially those targeting the central nervous system (CNS) and acting as enzyme inhibitors. This specific compound is notably used in the research and development of drugs for conditions such as depression, anxiety, and other neurological disorders. The Cbz protecting group allows for selective deprotection and further functionalization. As a high-value chiral intermediate, it is widely utilized in medicinal chemistry for constructing complex molecular architectures. Its availability in enantiomerically pure form is essential for producing single-enantiomer drugs, which often have superior efficacy and safety profiles compared to their racemic counterparts.
    Physical Properties

    Boiling Point: 382.5 °C at 760 mmHg

    Flash Point: 185.1 °C

    Density: 1.16g/cm3

    mg g kg ml l t