(R)-(-)-1,1,1-trifluoro-2-propanol, CAS No. 17628-73-8

Welcome to iChemical.com!

In the below part, please select the country you want us to ship to: Please note that once you've selected a shipping country, all pricing information on our website will be automatically updated to include door-to-door shipping to the country you specified.

North America

South America

Africa

Europe

Asia

Oceania

17628-73-8

Catalog No. EBD255910

CAS 17628-73-8

Name (R)-(-)-1,1,1-trifluoro-2-propanol

Get Quote

Basic Information

Synonyms: (R)-(-)-1,1,1-trifluoro-2-propanol (R)-1,1,1-Trifluoro-2-propanol (R)-1,1,1-trifluoro-propan-2-ol (2R)-1,1,1-trifluoropropane-2-ol (R)-1,1,1-trifluoropropanol (R)-Methyl-trifluormethyl-carbinol 2-Propanol,1,1,1-trifluoro-,(2R)-

Molecular Formula: C3H5F3O

Molecular Weight: 114.07

Categories: Synthetic Chemistry > Organic Building Blocks > Halogenated Compounds Synthetic Chemistry > Organic Building Blocks > Phenols and Ethers Materials Chemistry > Optoelectronic and Organic Semiconductor Materials > Liquid Crystal and Optically Active Small Molecule Precursors Synthetic Chemistry > Organic Building Blocks > Other Organic Building Blocks

Product Description:

(R)-(-)-1,1,1-Trifluoro-2-propanol is a chiral fluorinated alcohol featuring a trifluoromethyl group adjacent to a secondary hydroxyl group. Its high enantiomeric purity and strong electron-withdrawing CF3 moiety make it a versatile building block in asymmetric synthesis and medicinal chemistry. This compound is primarily utilized as a chiral solvating agent in NMR spectroscopy for determining enantiomeric purity of chiral compounds. It also serves as a key intermediate in the synthesis of fluorinated pharmaceuticals, agrochemicals, and liquid crystal materials, where the trifluoromethyl group enhances metabolic stability and lipophilicity. Additionally, it functions as a polar, non-reactive solvent or additive in organometallic reactions and peptide chemistry. Due to its volatility and low toxicity profile, it is preferred over other fluorinated alcohols in laboratory-scale transformations.

Physical Properties

Flash Point: 18 °C

Storage: 2-8°C

Safety Information

Packing Level: II

Hazard Category: 3

Transport Codes: 1987BE