(R)-2-amino-2-(4-fluorophenyl)ethanol, CAS No. 174770-74-2

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174770-74-2

Catalog No. EBD251001

CAS 174770-74-2

Name (R)-2-amino-2-(4-fluorophenyl)ethanol

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Basic Information

Synonyms: benzeneethanol,beta-amino-4-fluoro-,(betar)-(9ci) (r)-b-amino-4-fluoro-benzeneethanol benzeneethanol,beta-amino-4-fluoro-,(betar)- (2r)-2-amino-2-(4-fluorophenyl)ethan-1-ol (R)-2-amino-2-(4-fluorophenyl)ethanol (R)-(-)-2-(4-fluorophenyl)glycinol (R)-2-amino-2-(4-fluoro-phenyl)-ethanol (2R)-2-amino-2-(4-fluorophenyl)ethanol (R)-4-fluoro-phenylglycinol

Molecular Formula: C8H10FNO

Molecular Weight: 155.17

Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Chiral Intermediates Synthetic Chemistry > Organic Building Blocks > Amines

Product Description:

(R)-2-Amino-2-(4-fluorophenyl)ethanol is a chiral amino alcohol derivative featuring a 4-fluorophenyl group and a primary amino group. It serves as a crucial chiral building block in pharmaceutical synthesis. Its primary application is as a key intermediate in the production of chiral active pharmaceutical ingredients (APIs). Notably, it is a vital precursor in the synthesis of (R)-(-)-2-Amino-1-(4-fluorophenyl)ethanol, which is itself a key intermediate for the antidepressant drug (R)-(-)-Dapoxetine hydrochloride. The chiral integrity of this compound is essential for the biological activity of the final drug product. This compound is commercially available as a high-purity material for research and development purposes in medicinal chemistry. It exemplifies the importance of enantiomerically pure intermediates in modern asymmetric synthesis for drug discovery and manufacturing.

Physical Properties

Storage: −20°C