Butanoic acid,4-[(4-chlorophenyl)amino]-2,3-dihydroxy-4-oxo-, (2R,3R)-, CAS No. 17447-35-7

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17447-35-7

Catalog No. EBD3586410

CAS 17447-35-7

Name Butanoic acid,4-[(4-chlorophenyl)amino]-2,3-dihydroxy-4-oxo-, (2R,3R)-

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Basic Information

Synonyms: Butanoicacid,4-[(4-chlorophenyl)amino]-2,3-dihydroxy-4-oxo-,[R-(R*,R*)]- Tartranilicacid,4'-chloro-,(2R,3R)-(+)-(8CI) L-Tartaricacidp-chloroanilide Butanoicacid,4-[(4-chlorophenyl)amino]-2,3-dihydroxy-4-oxo-,(2R,3R)- (+)-4'-Chlorotartranilicacid 4-[(4-chlorophenyl)amino]-2,3-dihydroxy-4-oxobutanoicacid (2R,3R)-4-[(4-chlorophenyl)amino]-2,3-dihydroxy-4-oxobutanoicacid

Molecular Formula: C10H10ClNO5

Molecular Weight: 259.65

Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Heterocyclic Intermediates Medicinal Chemistry > Biochemicals and Life Science Reagents > Amino Acids and Derivatives

Product Description:

(2R,3R)-4-((4-Chlorophenyl)amino)-2,3-dihydroxy-4-oxobutanoic acid is a chiral organic compound featuring a butanoic acid backbone substituted with two hydroxyl groups and an N-(4-chlorophenyl)oxalamide moiety. Its structure contains both amino acid-like and aromatic amide functionalities, making it a valuable chiral building block. This compound is primarily utilized as a key intermediate in the synthesis of complex pharmaceutical agents. Its specific stereochemistry (2R,3R) is crucial for constructing molecules with defined biological activity. It serves as a precursor in the development of protease inhibitors and other therapeutic candidates where the chiral dihydroxybutanoate unit is a core structural motif. As a specialized chiral synthon, it is not a commodity chemical but is employed in targeted medicinal chemistry research and process development for active pharmaceutical ingredients (APIs). Handling requires standard laboratory precautions for organic compounds.

Physical Properties

Melting Point: 193 °C

Boiling Point: 609.1°Cat760mmHg

Flash Point: 322.2°C

Density: 1.644g/cm3