(R)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)pent-4-enoic acid, CAS No. 170642-28-1

Welcome to iChemical.com!

In the below part, please select the country you want us to ship to: Please note that once you've selected a shipping country, all pricing information on our website will be automatically updated to include door-to-door shipping to the country you specified.

North America

South America

Africa

Europe

Asia

Oceania

170642-28-1

Catalog No. EBD10340

CAS 170642-28-1

Name (R)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)pent-4-enoic acid

Get Quote

Basic Information

Synonyms: (R)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)pent-4-enoicacid (R)-N-Fmoc-Allylglycine Fmoc-(R)-2-Allylglycine Fmoc-D-2-Allylglycine Fmoc-D-Allylglycine Fmoc-D-(Allyl)Gly-Oh Fmoc-D-Algly-Oh Fmoc-D-Gly(Allyl)-Oh Fmoc-Alpha-Allyl-D-Gly Fmoc-Allyl-D-Glycine Fmoc-(R)-2-Amino-4-PentenoicAcid (2R)-2-{[(9H-Fluoren-9-Ylmethoxy)Carbonyl]Amino}Pent-4-Enoate fmoc-allyl-gly-oh (R)-N-(9-Fluorenylmethoxycarbonyl)-2-amino-4-pentenoicacid

Molecular Formula: C20H19NO4

Molecular Weight: 337.37

MDL Number: MFCD01311776

Categories: Medicinal Chemistry > Biochemicals and Life Science Reagents > Peptides and Peptidomimetics

Product Description:

Fmoc-D-allylglycine is a non-proteinogenic, D-configuration amino acid derivative. Its structure features an allyl side chain and is protected at the N-terminus by a 9-fluorenylmethoxycarbonyl (Fmoc) group, which is the standard protecting group used in solid-phase peptide synthesis (SPPS) employing the Fmoc/t-Bu strategy. This compound is primarily employed as a specialized building block in the synthesis of peptides and peptidomimetics. The incorporation of the D-allylglycine residue introduces conformational constraints and can impart resistance to enzymatic degradation, which is valuable in the design of bioactive peptides and potential therapeutic agents. The allyl side chain also offers a versatile chemical handle for further post-synthetic modifications, such as cross-metathesis or thiol-ene "click" chemistry, enabling the attachment of various functional groups or labels. As a protected amino acid derivative, it is a fundamental reagent in peptide chemistry research and pharmaceutical development. Its use is critical for constructing peptides with tailored properties for applications in drug discovery, biochemical probes, and structural biology studies.

Physical Properties

Melting Point: 134 °C

Boiling Point: 563 °C at 760 mmHg

Flash Point: 294.3 °C

Density: 1.245 g/cm3

Storage: 2-8°C

Analytical Data

Appearance: white granular powder