(R)-1-N-Boc-2-methylpiperazine, CAS No. 170033-47-3

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170033-47-3

Catalog No. EBD20190

CAS 170033-47-3

Name (R)-1-N-Boc-2-methylpiperazine

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Basic Information

Synonyms: (R)-1-N-Boc-2-MethylPiperazine (2R)-2-Methylpiperazine,N1-BOCprotected tert-Butyl(2R)-2-methylpiperazine-1-carboxylate (R)-1-Boc-2-methyl-piperazine (N)-1-N-Boc-2-methyl-piperazine (R)-1-Boc-2-methylpiperazine (2R)-2-methyl-1-Piperazinecarboxylicacid,1-dimethylethylester (r)-tert-butyl2-methylpiperazine-1-carboxylate (r)-2-methyl-piperazine-1-carboxylicacidtert-butylester (r)-2-methyl-1-boc-piperazine (S)-9-[(Dimethylamino)methyl]-6,7,10,11-tetrahydro-9H,18H-5,21:12,17-dimethenodibenzo[e,k]pyrrolo[3,4-h][1,4,13]oxadiazacyclohexadecine-18,20(19H)-dione LY333531 (2R)-2-methyl-1-Piperazi

Molecular Formula: C10H20N2O2

Molecular Weight: 200.28

MDL Number: MFCD01862120

Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Heterocyclic Intermediates Synthetic Chemistry > Organic Building Blocks > Amines

Product Description:

(R)-1-N-Boc-2-methylpiperazine is a chiral piperazine derivative characterized by a Boc-protected secondary amine and a methyl substituent at the 2-position. It serves as a crucial chiral building block in pharmaceutical synthesis. This compound is primarily employed as a key intermediate in the development of active pharmaceutical ingredients (APIs). Its chiral structure makes it valuable for constructing complex molecules, particularly in the synthesis of drugs targeting the central nervous system and other therapeutic areas. The Boc protecting group allows for selective deprotection and further functionalization during multi-step synthetic routes. As a versatile synthon, it is widely used in medicinal chemistry research and process development. Its applications extend to the synthesis of various bioactive molecules, highlighting its importance in modern drug discovery and manufacturing.

Physical Properties

Boiling Point: 268.7 °C at 760 mmHg

Flash Point: 116.3 °C

Density: 0.997 g/cm3