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    16937-91-0

    Catalog No. EBD2207920

    CAS 16937-91-0

    Name (R)-Nδ-benzyloxycarbonylornithine

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    Basic Information

    Synonyms: N5-[(Benzyloxy)carbonyl]-D-ornithine (R)-Nδ-benzyloxycarbonylornithine N-delta-cbz-D-ornithine H-D-Orn(Z)-OH

    Molecular Formula: C13H18N2O4

    Molecular Weight: 266.29

    MDL Number: MFCD00063115

    Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Drug Synthesis Building Blocks Medicinal Chemistry > Biochemicals and Life Science Reagents > Peptides and Peptidomimetics

    Product Description:
    N'-CBZ-D-Ornithine is a protected derivative of the non-proteinogenic amino acid D-ornithine. Its chemical structure features a D-configuration at the alpha-carbon and a carboxybenzyl (Cbz) protecting group on the side-chain amino group. This compound is a white to off-white crystalline powder. This derivative is primarily used as a key chiral building block in the solid-phase and solution-phase synthesis of peptides and peptidomimetics. The Cbz group protects the ornithine side chain during peptide assembly and can be selectively removed under mild hydrogenation conditions. D-Ornithine and its derivatives are of significant interest in medicinal chemistry for developing bioactive peptides, enzyme inhibitors, and potential therapeutic agents. As a protected amino acid, it serves as a crucial intermediate for researchers in pharmaceutical development and life sciences. Proper handling is required as it may cause skin and eye irritation.
    Physical Properties

    Boiling Point: 489.4 °C at 760 mmHg

    Flash Point: 249.8 °C

    Density: 1.234 g/cm3

    mg g kg ml l t