3-Hydroxy-4-methoxyaniline, CAS No. 1687-53-2

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1687-53-2

Catalog No. EBD955537

CAS 1687-53-2

Name 3-Hydroxy-4-methoxyaniline

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Basic Information

Synonyms: 5-Amino-2-methoxyphenol 1687-53-2 5-Aminoguaiacol Phenol,5-amino-2-methoxy- timtec-bbsbb007884 5-amino-2-methoxyphenol2-methoxy-5-aminophenol 5-amino-2-methyoxyphenol 3-Hydroxy-4-methoxyaniline 5-amino-2-methoxy-phenol 2-methoxy-5-aminophenol 3-hydroxy-4-methoxyphenylamine

Molecular Formula: C7H9NO2

Molecular Weight: 139.15

MDL Number: MFCD00010222

Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Heterocyclic Intermediates Synthetic Chemistry > Organic Building Blocks > Amines

Product Description:

5-Amino-2-methoxyphenol is an organic compound featuring both an amino group and a methoxy group attached to a phenol ring. It serves as a versatile chemical intermediate in organic synthesis. Its primary application is in the pharmaceutical industry, where it is used as a key building block for the synthesis of various active pharmaceutical ingredients (APIs). Notably, it is a crucial intermediate in the production of certain anti-inflammatory and analgesic drugs. The presence of both electron-donating groups makes it a valuable precursor for constructing more complex heterocyclic systems. Additionally, due to its bifunctional nature (amine and phenol), it finds use as a monomer or precursor in the synthesis of dyes, pigments, and specialty polymers. It is also employed in some hair dye formulations as a coupling agent.

Physical Properties

Melting Point: 130-132 °C(lit.)

Boiling Point: 292.7 °C at 760 mmHg

Flash Point: 130.8 °C

Density: 1.219 g/cm3

Solubility: slightly soluble

Analytical Data

Appearance: grey-brown to dark brown crystalline powder