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    168110-44-9

    Catalog No. EBD3319834

    CAS 168110-44-9

    Name Micafungin FR-179642 impurity (acid)

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    Basic Information

    Synonyms: MicafunginFR-179642impurity(acid) MicafunginFR-179642 FR179642

    Molecular Formula: C35H52N8O20S

    Molecular Weight: 936.89

    Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Other Pharmaceutical Intermediates Medicinal Chemistry > APIs and Their Salts > Anti-infectives

    Product Description:
    The compound with CAS number 168110-44-9 is a key synthetic intermediate in the production of micafungin sodium, a semisynthetic echinocandin antifungal agent. Micafungin is a potent and broad-spectrum antifungal drug used clinically to treat serious fungal infections, particularly invasive candidiasis and aspergillosis, by non-competitively inhibiting the synthesis of 1,3-β-D-glucan, an essential component of the fungal cell wall. This intermediate is a crucial building block in the complex multi-step synthesis of micafungin. Its structure is integral to forming the core cyclic hexapeptide framework of the final active pharmaceutical ingredient (API). The synthesis and purification of this intermediate are critical steps that directly impact the overall yield, purity, and cost-effectiveness of manufacturing the final drug substance. As a dedicated pharmaceutical intermediate, its primary and almost exclusive industrial application is in the synthesis of the antifungal API, micafungin. It is not a general-purpose chemical reagent or building block for other applications, underscoring its specialized role in the pharmaceutical supply chain for this specific antifungal medication.
    Physical Properties
    mg g kg ml l t